Scientist, Translational Sciences

At AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. Position Summary The Associate Scientist will help develop TCR-based immunotherapies for solid tumors within the Translational Sciences group. The Associate Scientist's work will support clinical biospecimen characterization and data quality control for clinical sample processing. You will be based onsite in Santa Monica, CA and report to a Scientist. We have multiple positions for candidates at various stages of their careers. Responsibilities Perform clinical biospecimen characterization, data analysis, and reporting of results in the form of presentations or written reports, following standard operating procedures (SOPs). Perform peer data audits and monitor data quality, in compliance with in-house and regulatory standards across multiple clinical programs. Collaborate with other Translational team members to ensure seamless data flow and reporting to address any discrepancies. Support design and qualification of cell-based functional assays. Document laboratory procedures and results with accuracy in an electronic laboratory notebook. Review and author SOPs, qualification reports, and other documents. Analyze, organize, and communicate results at different research and team meetings. Participate in project teams and work cross-functionally to ensure alignment. Other duties as assigned. Education and Experience Bachelor's with a minimum of 5 years or Master's with minimum of 2 years with a degree in immunology, cellular or tumor biology or in a relevant discipline with related lab or industry experience. Background in immunology or immunotherapy. Well-versed in cell culture aseptic techniques, multi-color flow cytometry (10+ colors), PCR, MSD/ELISA, or other cellular assays. Experience with spectral flow cytometry. Familiarity with working with large datasets and with associated data analysis and visualization software (i.e. Cytobank/OMIQ/FCS Express, Tableau/Spotfire/JMP). Ability to work in a dynamic environment. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. Date Posted : 15-Nov-2024 Closing Date : 21-Nov-2024

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