Bristol-Myers Squibb Company
Executive Director Discovery Metabolism and Pharmacokinetics
Bristol-Myers Squibb Company, Princeton, New Jersey, us, 08543
Executive Director Discovery Metabolism and Pharmacokinetics
Location:
Princeton, NJ, United States Employment Type:
Full-Time Posted on:
Jun 11, 2020 Profile Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience, and fibrosis. Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration, and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results. Responsibilities Lead a department of about 50 people, including Ph.D. scientists and research associates (BS or MS training). Current departmental expertise includes pharmacokinetics, PK-PD modeling and simulations, biotransformation, and xenobiotic transporter function and regulation. Lead scientific efforts to characterize metabolic fate and pharmacokinetic properties of drug candidates (small molecules, biologics, and novel modalities) to inform and direct lead optimization of drug candidates; proactively identify issues and enable investigative efforts that further enhance optimization of drug candidates. Encourage and facilitate research to advance new technologies and tools needed to develop screening strategies and/or refined approaches for drug disposition related issues. Represent Discovery Metabolism and Pharmacokinetics in strategic meetings and discussions with Discovery leadership to communicate potential liabilities and mitigation strategies. Engage in collaborative efforts with the scientific disciplines of the Pharmaceutical Candidate Optimization (PCO) organization (other areas are toxicology, pharmaceutics, and bioanalytical) to enable and develop broad-based strategies to advance programs into development. Interface with the Nonclinical Disposition Assessment Department (development function) and other stakeholders to ensure effective transitions from discovery into development. Education/Experience Ph.D. degree in any area of drug disposition, with emphasis on metabolism, pharmacokinetics, or biochemical toxicology. At least 15 years of experience (industry, academia, and/or government) in leading research efforts in drug metabolism and pharmacokinetics; preference to scientists who are familiar with advancing candidates from drug discovery to development. Experience leading a sophisticated drug metabolism and pharmacokinetic function in the effective application of novel DMPK approaches to accelerate drug discovery. Skills Required Strong background in drug disposition and related fields with emphasis on basic and applied metabolism and pharmacokinetic research in drug discovery. Strategic leadership ability to build and sustain scientific focus and Discovery portfolio support in drug metabolism with evidence for developing new leaders. Outstanding problem-solving skills, with proven ability to integrate across disciplines to address issues and identify mitigation strategies. Highly effective written and oral communication skills including contributions to the published literature. Ability to address technical issues with clarity and precision is essential. Strong interpersonal skills to enable an engaged, active research department. Demonstrated ability to mentor junior scientists and advance their professional development. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services, and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives. Company:
Bristol-Myers Squibb Req Number:
R1519523_EN Updated:
2020-01-13 00:00:00.000 UTC Location:
Princeton, New Jersey Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law. Company info Bristol-Myers Squibb Company Website:
http://www.bms.com
#J-18808-Ljbffr
Location:
Princeton, NJ, United States Employment Type:
Full-Time Posted on:
Jun 11, 2020 Profile Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience, and fibrosis. Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration, and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results. Responsibilities Lead a department of about 50 people, including Ph.D. scientists and research associates (BS or MS training). Current departmental expertise includes pharmacokinetics, PK-PD modeling and simulations, biotransformation, and xenobiotic transporter function and regulation. Lead scientific efforts to characterize metabolic fate and pharmacokinetic properties of drug candidates (small molecules, biologics, and novel modalities) to inform and direct lead optimization of drug candidates; proactively identify issues and enable investigative efforts that further enhance optimization of drug candidates. Encourage and facilitate research to advance new technologies and tools needed to develop screening strategies and/or refined approaches for drug disposition related issues. Represent Discovery Metabolism and Pharmacokinetics in strategic meetings and discussions with Discovery leadership to communicate potential liabilities and mitigation strategies. Engage in collaborative efforts with the scientific disciplines of the Pharmaceutical Candidate Optimization (PCO) organization (other areas are toxicology, pharmaceutics, and bioanalytical) to enable and develop broad-based strategies to advance programs into development. Interface with the Nonclinical Disposition Assessment Department (development function) and other stakeholders to ensure effective transitions from discovery into development. Education/Experience Ph.D. degree in any area of drug disposition, with emphasis on metabolism, pharmacokinetics, or biochemical toxicology. At least 15 years of experience (industry, academia, and/or government) in leading research efforts in drug metabolism and pharmacokinetics; preference to scientists who are familiar with advancing candidates from drug discovery to development. Experience leading a sophisticated drug metabolism and pharmacokinetic function in the effective application of novel DMPK approaches to accelerate drug discovery. Skills Required Strong background in drug disposition and related fields with emphasis on basic and applied metabolism and pharmacokinetic research in drug discovery. Strategic leadership ability to build and sustain scientific focus and Discovery portfolio support in drug metabolism with evidence for developing new leaders. Outstanding problem-solving skills, with proven ability to integrate across disciplines to address issues and identify mitigation strategies. Highly effective written and oral communication skills including contributions to the published literature. Ability to address technical issues with clarity and precision is essential. Strong interpersonal skills to enable an engaged, active research department. Demonstrated ability to mentor junior scientists and advance their professional development. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services, and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives. Company:
Bristol-Myers Squibb Req Number:
R1519523_EN Updated:
2020-01-13 00:00:00.000 UTC Location:
Princeton, New Jersey Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law. Company info Bristol-Myers Squibb Company Website:
http://www.bms.com
#J-18808-Ljbffr