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1910genetics

Research Associate - Biology

1910genetics, Boston, Massachusetts, us, 02298


Computation is revolutionizing drug discovery. Advances in big chemical data, massive computing power, artificial intelligence, and molecular dynamics simulation are changing the way we develop new drugs. At 1910 Genetics, we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, genetics, data science, and software engineering to develop drugs for previously undruggable targets.You are someone we can count on to...

Execute experiments effectively and efficientlyYour key responsibilities will include…

Executing high throughput screening (HTS) assays in strict accordance with the NIH NCATS Assay Guidance ManualDeveloping and validating HTS biochemical assays for characterizing the activity and selectivity of potential drug candidatesDeveloping and validating HTS cell-based assays for characterizing the activity, selectivity, and cellular permeability of potential drug candidatesPerforming a wide variety of experiments across molecular biology, cell biology, biochemistry, in vitro pharmacology, and in vivo pharmacologyRigorously documenting all experimental procedures, data, results, manuals, etc. in an electronic laboratory notebook (eLN)Leveraging internal and external personnel to troubleshoot experimentsEffectively communicating research results both verbally and orallyManaging all external CRO relationships, and cross-checking externally generated results with internal references and/or expectationsManaging all aspects of lab operations such as ordering, organizing, and restocking reagents, equipment, and other suppliesIdeally, you have…

B.S. or M.S. in Biology, Cell Biology, Molecular Biology, Biochemistry, Pharmacology, or equivalent0 – 3 years of laboratory experience in an industrial or academic settingExperience with or exposure to HTS assaysYou will learn…

Computational and Medicinal ChemistryAI/ML applied to drug discoveryYou will teach…

The NIH NCATS Assay Guidance Manual and HTS success criteria to your cross-disciplinary colleagues from Medicinal Chemistry, Computational Chemistry, AI Research, and Machine Learning EngineeringExtremely generous equity package coupled with competitive salary

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