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University of Utah

Manager, Laboratory

University of Utah, Salt Lake City, Utah, United States, 84193


We are looking for an exceptional candidate for a Laboratory Manager in a dynamic team exploring drug resistance, immunotherapy, and immunoprofiling in patients with cancer. The successful candidate will work under minimal supervision and is responsible for planning, organizing, directing, and/or controlling all aspects pertaining to laboratory functions including (but not limited to) specimen handling, data collection, process management, standard operating procedure development and adherence, data analyses, and outcomes monitoring. He/she will be responsible for performing and/or overseeing the steps needed to work with human cancer samples and cell lines and prepare libraries for comprehensive genomic sequencing. He/She will use fluorescent microscopy-based micromanipulation and flow cytometry and perform next-generation sequencing, including library preparation. He/She will work principally to meet production goals and requirements but will also seek to improve existing processes and/or innovate new approaches. The incumbent will be expected to work largely independently on a daily basis after training, but will coordinate closely with the principal investigator and others.Huntsman Cancer Institute is committed to cancer prevention, care, and survivorship for all communities within the area we serve – which includes Idaho, Montana, Nevada, Utah, and Wyoming – with impact worldwide.ResponsibilitiesEssential FunctionsSupervises and trains junior technicians and ensures competency of staff through hands-on supervision and training.Manages inventory of biological samples.Prepares, orders, and maintains stocks of required reagents and supplies.Seeks to improve existing processes, develops standard operating procedures, and evaluates new approaches.Troubleshoots protocols as needed.Operates and maintains laboratory equipment to complete investigations.Prepares primary human blood and tumor samples for further processing.Handles sensitive primary human cells and uses established protocols while working closely with core facilities and collaborators.Performs isolation of circulating tumor cells and other single cells using fluorescent microscopy-based micromanipulation, flow cytometry, and other techniques.Operates next-generation sequencing machines and prepares libraries for next-generation sequencing.Documents, compiles, and analyzes experimental protocols and data.Attends team meetings to share results, plan projects, and experiments.Other related tasks as required.Problem-SolvingMust possess a high level of initiative and the ability to work with little supervision while adhering to Standard Operating Procedures.Must have excellent written, documentation, and oral communication skills.Must possess strong interpersonal, organizational, and analytical skills, including the ability to handle a variety of tasks in a fast-paced environment.Proactive in identifying problems and solutions to address them.Must be an exceptional team player.Minimum QualificationsRequires a Bachelor’s degree in a related area of assignment or equivalency (one year of education can be substituted for two years of related work experience) and 4 – 6 years of progressively more responsible management experience. Background knowledge of assigned department’s area of specialization in order to analyze, plan, and draw conclusions for recommendations to superiors. Demonstrated leadership skills in planning and directing employees and processes to effectively monitor and develop subordinates and to ensure the smooth operation of the department. Completion of provided supervisory training within one year of employment may be required. Master’s degree in a related area may be preferred.Applicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description.PreferencesFamiliarity with fluorescent microscopy or flow cytometry is required.Experience with molecular biology techniques such as PCR and/or sequencing library construction required.Familiarity or experience with next-generation sequencing and library preparation preferred.Working knowledge of computers required; familiarity with computer programming preferred.Work Environment and Level of Frequency that may be requiredNearly Continuously: Office environment.Physical Requirements and Level of Frequency that may be requiredNearly Continuously: Sitting, hearing, listening, talking. Often: Repetitive hand motion (such as typing), walking. Seldom: Bending, reaching overhead.This job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to the job.

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