Head of Translational Medicine

The Head of Translational Medicine would oversee the translational medicine initiatives, particularly focusing on the integration of imaging biomarkers, particularly MRI outcomes, into our development programs. This individual would be responsible for driving the translational strategy from preclinical stages through clinical trials, ensuring that innovative imaging techniques are effectively applied to enhance our understanding of therapeutics efficacy, especially in muscle and cardiac tissue.Primary Responsibilities IncludeLead the translational strategy for the integration of imaging biomarkers into both preclinical and clinical development programs.Collaborate closely with cross-functional teams to align translational medicine goals with overall development objectives.Drive reverse translation by leveraging clinical trial data to inform preclinical research, particularly focusing on mechanism studies and hypothesis testing.Provide scientific leadership in the application of MRI technology for muscle and cardiac imaging within the context of biomarker discovery and development, including external collaborations that use imaging biomarkers to define disease natural history.Develop and implement strategies to incorporate advanced imaging biomarkers into clinical protocols, ensuring alignment with regulatory and clinical endpoints.Oversee the design and execution of preclinical and clinical studies involving imaging biomarkers, ensuring high standards of scientific rigor and data quality.Act as a scientific and strategic liaison with external partners, including key opinion leaders and regulatory bodies, to drive the successful implementation of imaging technologies in drug development.Identify and champion novel imaging techniques and digital biomarkers that can be integrated into the drug development process to enhance patient selection, treatment monitoring, and therapeutic outcomes.Ensure continuous improvement of translational methodologies by staying abreast of emerging technologies and scientific advancements.Desired Education And SkillsMD or PhD in a relevant field such as Radiology, Medical Imaging, or Biomedical Sciences.A minimum of 11+ years of experience in the biopharma or biotechnology industry or relevant academic experience, with a proven track record in translational medicine or imaging biomarker development.Extensive experience in MRI technology with a strong focus on muscle and cardiac imaging.Demonstrated ability to lead cross-functional teams in a matrix environment and effectively collaborate with external partners.Strong understanding of the regulatory landscape and experience in preparing and submitting regulatory documents.Excellent communication and leadership skills, with the ability to influence and drive projects forward in a fast-paced environment.This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time.The targeted salary range for this position is $248,000 – $310,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S.Sarepta Therapeutics offers a competitive compensation and benefit package.Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

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