Takeda Pharmaceutical
Research Scientist, Liver Disease
Takeda Pharmaceutical, Boston, Massachusetts, United States, 02203
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true to the best of my knowledge.
Job DescriptionResearch Scientist, Liver DiseaseAbout the role:At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Research Scientist, Liver Disease Research where you will be part of a team focused on validation of novel targets and the evaluation of drug candidates for the treatment of chronic fibroinflammatory liver diseases.How you will contribute:You will apply expertise in executing in vitro studies relevant to fibroinflammatory liver disease biology and pharmacology.You will play a central role in generating key data for evaluating potential targets, mechanism of action and/or drug candidate efficacy and pharmacodynamics.You will need to be a highly collaborative and energetic team player and a self-directed learner with a keen interest in focused, fast-paced research.Designs and executes relevant target and drug candidate validation studies using contemporary methods and tools.Using a broad range of technologies, determine mechanism of action for drug targets and candidates with appropriate controlsImplement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriateIdentifies orthogonal applications of target, pathway, or platform biology in other fibroinflammatory diseasesParticipate on cross-functional teams and provide technical leadership in area of expertise; may lead an initiative or one of a broader scope with a less-defined outcomePrepare technical reports, summaries, protocols, and quantitative analyses in written and/or oral formProactively identify complex obstacles to progress in specific areas; recommend and implement solutions using a diverse set of resources; regularly add value to research projects through creative ideasManage a wide variety of tasks, techniques, and projects; integrate these responsibilities to produce quality result with a high level of efficiency; may act as a scientific mentor to othersKeep an accurate, comprehensible, concise notebook in accordance with company policyMaintain lab equipment and supplies as neededMaintain a safe and organized lab benchCommunicate with colleagues effectivelyPresent data to other scientific staff or cross-functional project team; may present data/posters to external research or scientific community.Minimum
Requirements/Qualifications:PhD degree in a scientific discipline (or equivalent), orMS with 6+ years relevant experience, or BS with 8+ years relevant experience in vitro drug discovery researchDemonstrated ability to independently solve scientific problems using multiple, state-of-the-art technologies and approachesSignificant experience with drug discovery applications of cell culture including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissuesExpertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIPExperience and continued willingness to work with live rodents and animal tissueDemonstrates exceptional project management skills and in-depth in vitro cell and molecular biology assay experience
Takeda Compensation and Benefits Summary
We understand compensation is
an important factor
as you consider the next step in your career. We are committed to
equitable
pay for all employees, and we strive to be more transparent with our pay practices.
For Location:Boston, MAU.S. Base Salary Range:$108,500.00 - $170,500.00The estimated salary range reflects
an anticipated
range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education
attained
, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
?
The actual base salary offered will be
in accordance with
state or local minimum wage requirements for the job location.
U.S. based
e
mployee
s
may be eligible for
s
hort
-
t
erm and/
or
l
ong-
t
erm
incentive
s
.
U.S.
based employees
may be
eligible to
participate
in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and
well-being
benefits, among others. U.S.
based employees are also eligible to receive, per calendar year, up to
80 hours
of sick time, and new hires are eligible to
accrue
up to
120 hours of paid vacation.
EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
LocationsBoston, MA
Worker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time By applying, you consent to your information being transmitted by Jobcase to the Employer, as data controller, through the Employers data processor SonicJobs.See Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions
the information I provide in my application will be processed in line with
Takedas
Privacy Notice
and
Terms of Use .
I further attest that all information I submit in my employment application
is
true to the best of my knowledge.
Job DescriptionResearch Scientist, Liver DiseaseAbout the role:At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Research Scientist, Liver Disease Research where you will be part of a team focused on validation of novel targets and the evaluation of drug candidates for the treatment of chronic fibroinflammatory liver diseases.How you will contribute:You will apply expertise in executing in vitro studies relevant to fibroinflammatory liver disease biology and pharmacology.You will play a central role in generating key data for evaluating potential targets, mechanism of action and/or drug candidate efficacy and pharmacodynamics.You will need to be a highly collaborative and energetic team player and a self-directed learner with a keen interest in focused, fast-paced research.Designs and executes relevant target and drug candidate validation studies using contemporary methods and tools.Using a broad range of technologies, determine mechanism of action for drug targets and candidates with appropriate controlsImplement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriateIdentifies orthogonal applications of target, pathway, or platform biology in other fibroinflammatory diseasesParticipate on cross-functional teams and provide technical leadership in area of expertise; may lead an initiative or one of a broader scope with a less-defined outcomePrepare technical reports, summaries, protocols, and quantitative analyses in written and/or oral formProactively identify complex obstacles to progress in specific areas; recommend and implement solutions using a diverse set of resources; regularly add value to research projects through creative ideasManage a wide variety of tasks, techniques, and projects; integrate these responsibilities to produce quality result with a high level of efficiency; may act as a scientific mentor to othersKeep an accurate, comprehensible, concise notebook in accordance with company policyMaintain lab equipment and supplies as neededMaintain a safe and organized lab benchCommunicate with colleagues effectivelyPresent data to other scientific staff or cross-functional project team; may present data/posters to external research or scientific community.Minimum
Requirements/Qualifications:PhD degree in a scientific discipline (or equivalent), orMS with 6+ years relevant experience, or BS with 8+ years relevant experience in vitro drug discovery researchDemonstrated ability to independently solve scientific problems using multiple, state-of-the-art technologies and approachesSignificant experience with drug discovery applications of cell culture including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissuesExpertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIPExperience and continued willingness to work with live rodents and animal tissueDemonstrates exceptional project management skills and in-depth in vitro cell and molecular biology assay experience
Takeda Compensation and Benefits Summary
We understand compensation is
an important factor
as you consider the next step in your career. We are committed to
equitable
pay for all employees, and we strive to be more transparent with our pay practices.
For Location:Boston, MAU.S. Base Salary Range:$108,500.00 - $170,500.00The estimated salary range reflects
an anticipated
range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education
attained
, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
?
The actual base salary offered will be
in accordance with
state or local minimum wage requirements for the job location.
U.S. based
e
mployee
s
may be eligible for
s
hort
-
t
erm and/
or
l
ong-
t
erm
incentive
s
.
U.S.
based employees
may be
eligible to
participate
in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and
well-being
benefits, among others. U.S.
based employees are also eligible to receive, per calendar year, up to
80 hours
of sick time, and new hires are eligible to
accrue
up to
120 hours of paid vacation.
EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
LocationsBoston, MA
Worker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time By applying, you consent to your information being transmitted by Jobcase to the Employer, as data controller, through the Employers data processor SonicJobs.See Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions