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CK Group

Scientist Antibody Job at CK Group in Waltham

CK Group, Waltham, Massachusetts, us


Scientist, Antibody

Join a cutting-edge, clinical-stage precision immuno-oncology company focused on developing breakthrough treatments for solid tumors and hematological malignancies. This full-time, permanent role offers the opportunity to contribute to the advancement of a leading program developed by renowned scientists from Dana Farber, MGH, the Broad, and MIT. With over $120M raised from top-tier investors, the company is driving its clinical pipeline forward while expanding and validating novel therapeutic programs.

Job Summary:

We are seeking a talented scientist with expertise in antibody discovery, engineering, and characterization. Reporting to the Senior Director of Antibodies, the successful candidate will play a pivotal role in discovering and optimizing therapeutic antibodies. This is a primarily lab-based position, with opportunities to collaborate on project teams, interact with CRO partners, and contribute to strategic decision-making.

Key Responsibilities:Design, construct, and screen antibody libraries to identify or optimize antibodies with desired properties.Conduct biophysical characterization of antibodies.Collaborate closely with the Biology group to accelerate program advancement.Present and communicate research findings in group and project meetings.Maintain thorough documentation of experimental work in electronic lab notebooks.

Qualifications & Education Requirements:BS with 5+ years, MS with 3+ years, or PhD in a relevant field (title will be based on experience).Proven hands-on experience with yeast display and/or phage display.Expertise in antibody affinity maturation, humanization, and related techniques.Skilled in antibody biophysical characterization methods such as ELISA, binding kinetics (Octet/SPR), flow cytometry, DSF, and more.Experience with alternative antibody formats like single-domain or bispecific antibodies is a plus.Strong knowledge of therapeutic antibody development.Ability to work independently, designing, executing, and troubleshooting experiments with minimal supervision.A collaborative team player with excellent verbal and written communication skills, capable of thriving in a fast-paced environment.

Additional Information:

Candidates must have the right to work in the U.S. and be available to start immediately.

Apply:

Please quote job reference 107530 in all correspondence.