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PostEra

Reproductive Endocrinologist (eq. Principal Scientist)

PostEra, Boston, Massachusetts, us, 02298


[Full Time] Reproductive Endocrinologist (eq. Principal Scientist) at PostEra (United States)Reproductive Endocrinologist (eq. Principal Scientist)

PostEra United StatesDate Posted: 02 Aug, 2023Work Location: Boston, United StatesSalary Offered: $150000 — $200000 yearlyJob Type: Full TimeExperience Required: 3+ yearsRemote Work: NoStock Options: YesVacancies: 1 availablePostEra is building a modern biopharma, using machine learning to accelerate medicinal chemistry, to develop cures for diseases, faster. We've raised $26M from top investors, secured a $68M NIH partnership to prevent pandemics, and established a $260M partnership with Pfizer. We also launched and help lead the world's largest open-science initiative to find a COVID antiviral; COVID Moonshot.PostEra pioneered many of the advances in AI for Medicinal Chemistry and uses its platform to drive drug discovery projects from Target to Development Candidate. In addition to multi-year deals with partners like Pfizer and the NIH, we are now building internal drug discovery capabilities and an internal portfolio in Women’s Health and Reproductive Medicine.What you would do

Biology Lead on multiple programs, from target validation to lead optimization.Implement biology capabilities associated with PostEra’s targets from

in vitro

pharmacology, biology to

in vivo

efficacy models.Manage implementation and execution of key experiments at multiple CROs and analyze and report data to internal team.Assist the Head of Biology in building in-house capabilities, including

in vivo

pharmacology capabilities.Work closely with ML researchers on building target ID tools.Work closely with the Head of Biology and CSO to identify and evaluate targets for Women’s Health and Reproductive Medicine.Build the strategy associated with targets of interest, from market research to target product profile, define assay cascade and critical Go/No Go.Experience and skills you should have

PhD in biology or related discipline with >4 years industry experience in the field of Reproductive Endocrinology, Reproductive Biology, Fertility, Uterine/Gonadal Biology, Neuroendocrinology or related field.Broad experience in disease biology, mechanistic understanding of pathways and translational

in vitro

AND

in vivo

models and tools relevant for research in fertility and reproductive medicine (Preferably PCOS, endometriosis and/or other male and female infertility disorders).Excellent skills in

in vivo

pharmacology, developing disease models for both target validation and evaluation of efficacy and toxicity of lead molecules.Adept at navigating and influencing a multi-disciplinary matrix environment.Excellent interpersonal and communication skills, oral and written.Willing to travel up to 10% annually.Bonus experience and skills

Experience working with non-human primates a plus.Experience with basic rodent surgery a plus.Expertise in Histology strongly preferred.Experience with metabolic disorders a plus.Expertise in Molecular Pharmacology and development of biochemical and cell-based assays strongly preferred.Salary: 150k - 200kEquity: 0.10% - 0.20%Visa Sponsorship: Not at this timeHiring Manager:

Marie-Laure RivesVisit us at postera.aiAbout PostEra

Medicinal Chemistry powered by Machine Learning

Company Size:

11 - 50 PeopleYear Founded:

2019Country:

United StatesCompany Status:

Actively Hiring

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